go_id,ontology,go_term,term_definition,evidence GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA GO:0005741,CC,"mitochondrial outer membrane","The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.",IDA GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA GO:0043457,BP,"regulation of cellular respiration","Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.",IEA GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA GO:0051537,MF,"2 iron, 2 sulfur cluster binding","Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.",IDA GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA