go_id,ontology,go_term,term_definition,evidence
GO:0005262,MF,"calcium channel activity","Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.",TAS
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005516,MF,"calmodulin binding","Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.",IEA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0005887,CC,"integral component of plasma membrane","The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IDA
GO:0006816,BP,"calcium ion transport","The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ISS
GO:0017158,BP,"regulation of calcium ion-dependent exocytosis","Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.",IBA
GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA
GO:0051592,BP,"response to calcium ion","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.",IEA
GO:0055074,BP,"calcium ion homeostasis","Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:0070588,BP,"calcium ion transmembrane transport","A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.",IDA
GO:1990035,BP,"calcium ion import into cell","The directed movement of calcium ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.",IDA