go_id,ontology,go_term,term_definition,evidence GO:0005089,MF,"Rho guanyl-nucleotide exchange factor activity","Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.",IDA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0035023,BP,"regulation of Rho protein signal transduction","Any process that modulates the frequency, rate or extent of Rho protein signal transduction.",IEA GO:0043547,BP,"positive regulation of GTPase activity","Any process that activates or increases the activity of a GTPase.",IEA