go_id,ontology,go_term,term_definition,evidence GO:0004722,MF,"protein serine/threonine phosphatase activity","Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.",IEA GO:0004725,MF,"protein tyrosine phosphatase activity","Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.",IBA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0008138,MF,"protein tyrosine/serine/threonine phosphatase activity","Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.",IEA GO:0016311,BP,dephosphorylation,"The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.",IEA GO:0016791,MF,"phosphatase activity","Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.",IDA GO:0035335,BP,"peptidyl-tyrosine dephosphorylation","The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.",IEA GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA