go_id,ontology,go_term,term_definition,evidence GO:0000398,BP,"mRNA splicing, via spliceosome","The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.",IGI GO:0003723,MF,"RNA binding","Interacting selectively and non-covalently with an RNA molecule or a portion thereof.",IEA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0005847,CC,"mRNA cleavage and polyadenylation specificity factor complex","A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.",IDA GO:0006369,BP,"termination of RNA polymerase II transcription","The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.",TAS GO:0006378,BP,"mRNA polyadenylation","The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.",IMP GO:0006379,BP,"mRNA cleavage","Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.",IDA GO:0006398,BP,"mRNA 3'-end processing by stem-loop binding and cleavage","Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.",ISS GO:0006406,BP,"mRNA export from nucleus","The directed movement of mRNA from the nucleus to the cytoplasm.",IGI GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA GO:0031124,BP,"mRNA 3'-end processing","Any process involved in forming the mature 3' end of an mRNA molecule.",TAS