go_id,ontology,go_term,term_definition,evidence
GO:0000045,BP,"autophagosome assembly","The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.",IMP
GO:0003924,MF,"GTPase activity","Catalysis of the reaction: GTP + H2O = GDP + phosphate.",IEA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005525,MF,"GTP binding","Interacting selectively and non-covalently with GTP, guanosine triphosphate.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005776,CC,autophagosome,"A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the vacuole/lysosome for degradation as part of macroautophagy.",ISS
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0006968,BP,"cellular defense response","A defense response that is mediated by cells.",TAS
GO:0007264,BP,"small GTPase mediated signal transduction","Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.",IEA
GO:0010008,CC,"endosome membrane","The lipid bilayer surrounding an endosome.",TAS
GO:0015031,BP,"protein transport","The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",IEA
GO:0030670,CC,"phagocytic vesicle membrane","The lipid bilayer surrounding a phagocytic vesicle.",TAS
GO:0042384,BP,"cilium assembly","The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.",IMP
GO:0042992,BP,"negative regulation of transcription factor import into nucleus","Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.",IEA
GO:0045335,CC,"phagocytic vesicle","A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:0097094,BP,"craniofacial suture morphogenesis","The process in which any suture between cranial and/or facial bones is generated and organized.",IEA