go_id,ontology,go_term,term_definition,evidence GO:0000978,MF,"RNA polymerase II core promoter proximal region sequence-specific DNA binding","Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.",IDA GO:0001077,MF,"transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding","Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.",IEA GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0006366,BP,"transcription from RNA polymerase II promoter","The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).",TAS GO:0030307,BP,"positive regulation of cell growth","Any process that activates or increases the frequency, rate, extent or direction of cell growth.",IMP GO:0043621,MF,"protein self-association","Interacting selectively and non-covalently with a domain within the same polypeptide.",IPI GO:0043922,BP,"negative regulation by host of viral transcription","Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.",IDA GO:0043923,BP,"positive regulation by host of viral transcription","Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.",IMP GO:0044212,MF,"transcription regulatory region DNA binding","Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.",IDA GO:0045892,BP,"negative regulation of transcription, DNA-templated","Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.",ISS GO:0045944,BP,"positive regulation of transcription from RNA polymerase II promoter","Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IMP GO:0046718,BP,"viral entry into host cell","The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.",TAS GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA