go_id,ontology,go_term,term_definition,evidence
GO:0005085,MF,"guanyl-nucleotide exchange factor activity","Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.",IEA
GO:0005089,MF,"Rho guanyl-nucleotide exchange factor activity","Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.",IDA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005622,CC,intracellular,"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.",IEA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0007266,BP,"Rho protein signal transduction","A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.",TAS
GO:0035023,BP,"regulation of Rho protein signal transduction","Any process that modulates the frequency, rate or extent of Rho protein signal transduction.",IEA
GO:0043065,BP,"positive regulation of apoptotic process","Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.",ISS
GO:0043547,BP,"positive regulation of GTPase activity","Any process that activates or increases the activity of a GTPase.",IEA
GO:0051056,BP,"regulation of small GTPase mediated signal transduction","Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.",TAS