go_id,ontology,go_term,term_definition,evidence GO:0001525,BP,angiogenesis,"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.",IEA GO:0005201,MF,"extracellular matrix structural constituent","The action of a molecule that contributes to the structural integrity of the extracellular matrix.",IBA GO:0005576,CC,"extracellular region","The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.",IEA GO:0005587,CC,"collagen type IV trimer","A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.",TAS GO:0005788,CC,"endoplasmic reticulum lumen","The volume enclosed by the membranes of the endoplasmic reticulum.",IDA GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA GO:0016525,BP,"negative regulation of angiogenesis","Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.",IMP GO:0030198,BP,"extracellular matrix organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.",IEA GO:0030574,BP,"collagen catabolic process","The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.",TAS GO:0031012,CC,"extracellular matrix","A structure lying external to one or more cells, which provides structural support for cells or tissues.",IDA|ISS GO:0035987,BP,"endodermal cell differentiation","The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.",IEA GO:0043231,CC,"intracellular membrane-bounded organelle","Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",IDA GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA GO:0071560,BP,"cellular response to transforming growth factor beta stimulus","Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.",IDA