go_id,ontology,go_term,term_definition,evidence
GO:0003779,MF,"actin binding","Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.",IEA
GO:0005516,MF,"calmodulin binding","Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.",IEA
GO:0005856,CC,cytoskeleton,"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.",IBA
GO:0005925,CC,"focal adhesion","Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.",IDA
GO:0006940,BP,"regulation of smooth muscle contraction","Any process that modulates the frequency, rate or extent of smooth muscle contraction.",TAS
GO:0031032,BP,"actomyosin structure organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.",IBA
GO:1904706,BP,"negative regulation of vascular smooth muscle cell proliferation","Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.",IEA