go_id,ontology,go_term,term_definition,evidence GO:0000932,CC,"cytoplasmic mRNA processing body","A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.",IEA GO:0003690,MF,"double-stranded DNA binding","Interacting selectively and non-covalently with double-stranded DNA.",IDA GO:0003725,MF,"double-stranded RNA binding","Interacting selectively and non-covalently with double-stranded RNA.",IDA|NAS GO:0003727,MF,"single-stranded RNA binding","Interacting selectively and non-covalently with single-stranded RNA.",IBA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0006417,BP,"regulation of translation","Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.",IEA GO:0007275,BP,"multicellular organism development","The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",IEA GO:0010494,CC,"cytoplasmic stress granule","A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.",IDA GO:0033962,BP,"cytoplasmic mRNA processing body assembly","The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.",IBA GO:0039529,BP,"RIG-I signaling pathway","Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.",IEA GO:0043231,CC,"intracellular membrane-bounded organelle","Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",IDA GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA GO:0060340,BP,"positive regulation of type I interferon-mediated signaling pathway","Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.",IDA