go_id,ontology,go_term,term_definition,evidence GO:0004674,MF,"protein serine/threonine kinase activity","Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",IBA GO:0004712,MF,"protein serine/threonine/tyrosine kinase activity","Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.",TAS GO:0004713,MF,"protein tyrosine kinase activity","Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.",IEA GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0016323,CC,"basolateral plasma membrane","The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.",IEA GO:0016324,CC,"apical plasma membrane","The region of the plasma membrane located at the apical end of the cell.",IEA GO:0018108,BP,"peptidyl-tyrosine phosphorylation","The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.",IEA GO:0030054,CC,"cell junction","A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.",IEA GO:0033674,BP,"positive regulation of kinase activity","Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",IDA GO:0044344,BP,"cellular response to fibroblast growth factor stimulus","Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.",IDA GO:0045743,BP,"positive regulation of fibroblast growth factor receptor signaling pathway","Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.",IEA GO:0070374,BP,"positive regulation of ERK1 and ERK2 cascade","Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.",IEA