go_id,ontology,go_term,term_definition,evidence
GO:0000060,BP,"protein import into nucleus, translocation","A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.",IBA
GO:0000082,BP,"G1/S transition of mitotic cell cycle","The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.",TAS
GO:0000722,BP,"telomere maintenance via recombination","Any recombinational process that contributes to the maintenance of proper telomeric length.",IEA
GO:0003674,MF,molecular_function,"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.",ND
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003887,MF,"DNA-directed DNA polymerase activity","Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005658,CC,"alpha DNA polymerase:primase complex","A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.",IDA|TAS
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0006260,BP,"DNA replication","The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.",TAS
GO:0006270,BP,"DNA replication initiation","The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.",IBA
GO:0006271,BP,"DNA strand elongation involved in DNA replication","The process in which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand.",IMP|TAS
GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI
GO:0071897,BP,"DNA biosynthetic process","The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.",IEA