go_id,ontology,go_term,term_definition,evidence GO:0000786,CC,nucleosome,"A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.",NAS GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA GO:0004402,MF,"histone acetyltransferase activity","Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.",IDA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0006334,BP,"nucleosome assembly","The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",IDA GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA GO:0008134,MF,"transcription factor binding","Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.",IBA GO:0008270,MF,"zinc ion binding","Interacting selectively and non-covalently with zinc (Zn) ions.",IEA GO:0016407,MF,"acetyltransferase activity","Catalysis of the transfer of an acetyl group to an acceptor molecule.",EXP|IDA|IMP GO:0016573,BP,"histone acetylation","The modification of a histone by the addition of an acetyl group.",IEA GO:0032403,MF,"protein complex binding","Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IEA GO:0043966,BP,"histone H3 acetylation","The modification of histone H3 by the addition of an acetyl group.",IDA GO:0045892,BP,"negative regulation of transcription, DNA-templated","Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.",ISS GO:0045893,BP,"positive regulation of transcription, DNA-templated","Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.",IDA GO:0045944,BP,"positive regulation of transcription from RNA polymerase II promoter","Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IMP GO:0070776,CC,"MOZ/MORF histone acetyltransferase complex","A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.",IDA