go_id,ontology,go_term,term_definition,evidence
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA
GO:0008013,MF,"beta-catenin binding","Interacting selectively and non-covalently with the beta subunit of the catenin complex.",IEA
GO:0010977,BP,"negative regulation of neuron projection development","Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).",IDA
GO:0030177,BP,"positive regulation of Wnt signaling pathway","Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.",IMP
GO:0030336,BP,"negative regulation of cell migration","Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.",TAS
GO:0030837,BP,"negative regulation of actin filament polymerization","Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.",IDA
GO:0032587,CC,"ruffle membrane","The portion of the plasma membrane surrounding a ruffle.",IEA
GO:0035024,BP,"negative regulation of Rho protein signal transduction","Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.",IEA
GO:0035413,BP,"positive regulation of catenin import into nucleus","Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.",IMP
GO:0046627,BP,"negative regulation of insulin receptor signaling pathway","Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.",IBA
GO:0090303,BP,"positive regulation of wound healing","Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.",IC
GO:1900025,BP,"negative regulation of substrate adhesion-dependent cell spreading","Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.",IDA
GO:1900028,BP,"negative regulation of ruffle assembly","Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.",IDA
GO:2000114,BP,"regulation of establishment of cell polarity","Any process that modulates the frequency, rate or extent of establishment of cell polarity.",IMP
GO:2000393,BP,"negative regulation of lamellipodium morphogenesis","Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.",IDA