go_id,ontology,go_term,term_definition,evidence
GO:0000775,CC,"chromosome, centromeric region","The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.",TAS
GO:0000785,CC,chromatin,"The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.",IEA
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005694,CC,chromosome,"A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.",IEA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0006281,BP,"DNA repair","The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.",IEA
GO:0007062,BP,"sister chromatid cohesion","The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.",TAS
GO:0007064,BP,"mitotic sister chromatid cohesion","The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.",IBA
GO:0008283,BP,"cell proliferation","The multiplication or reproduction of cells, resulting in the expansion of a cell population.",IEA
GO:0008285,BP,"negative regulation of cell proliferation","Any process that stops, prevents or reduces the rate or extent of cell proliferation.",NAS
GO:0042127,BP,"regulation of cell proliferation","Any process that modulates the frequency, rate or extent of cell proliferation.",IBA
GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA