go_id,ontology,go_term,term_definition,evidence
GO:0001649,BP,"osteoblast differentiation","The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.",IEA
GO:0005518,MF,"collagen binding","Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).",IEA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0005925,CC,"focal adhesion","Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.",IDA
GO:0006929,BP,"substrate-dependent cell migration","The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.",IMP
GO:0007155,BP,"cell adhesion","The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.",IEA
GO:0007160,BP,"cell-matrix adhesion","The binding of a cell to the extracellular matrix via adhesion molecules.",IDA
GO:0007229,BP,"integrin-mediated signaling pathway","A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.",NAS
GO:0007517,BP,"muscle organ development","The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.",ISS
GO:0008305,CC,"integrin complex","A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.",TAS
GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA
GO:0030198,BP,"extracellular matrix organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.",IEA
GO:0033627,BP,"cell adhesion mediated by integrin","The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.",IDA
GO:0034681,CC,"integrin alpha11-beta1 complex","An integrin complex that comprises one alpha11 subunit and one beta1 subunit.",IDA
GO:0038064,MF,"collagen receptor activity","Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",IMP
GO:0038065,BP,"collagen-activated signaling pathway","A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription.",IMP
GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA
GO:0098639,MF,"collagen binding involved in cell-matrix adhesion","Any collagen binding that occurs as part of cell-matrix adhesion.",IMP