go_id,ontology,go_term,term_definition,evidence
GO:0000287,MF,"magnesium ion binding","Interacting selectively and non-covalently with magnesium (Mg) ions.",IDA
GO:0004674,MF,"protein serine/threonine kinase activity","Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",IBA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005913,CC,"cell-cell adherens junction","An adherens junction which connects a cell to another cell.",IDA
GO:0006464,BP,"cellular protein modification process","The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).",TAS
GO:0006468,BP,"protein phosphorylation","The process of introducing a phosphate group on to a protein.",NAS
GO:0018105,BP,"peptidyl-serine phosphorylation","The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.",IBA
GO:0031435,MF,"mitogen-activated protein kinase kinase kinase binding","Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.",IPI
GO:0035556,BP,"intracellular signal transduction","The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.",IEA
GO:0043407,BP,"negative regulation of MAP kinase activity","Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.",IEA
GO:0070688,CC,"MLL5-L complex","A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively.",IDA
GO:0098609,BP,"cell-cell adhesion","The attachment of one cell to another cell via adhesion molecules.",IEA
GO:0098641,MF,"cadherin binding involved in cell-cell adhesion","Any cadherin binding that occurs as part of the process of cell-cell adhesion.",IDA