go_id,ontology,go_term,term_definition,evidence
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005815,CC,"microtubule organizing center","An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.",IDA
GO:0005925,CC,"focal adhesion","Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.",IDA
GO:0007067,BP,"mitotic nuclear division","A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",IEA
GO:0015629,CC,"actin cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.",ISS
GO:0017049,MF,"GTP-Rho binding","Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.",IDA
GO:0030047,BP,"actin modification","Covalent modification of an actin molecule.",NAS
GO:0030496,CC,midbody,"A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.",TAS
GO:0031625,MF,"ubiquitin protein ligase binding","Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.",IBA
GO:0045159,MF,"myosin II binding","Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.",NAS
GO:0051015,MF,"actin filament binding","Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.",IBA
GO:0051016,BP,"barbed-end actin filament capping","The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.",IEA
GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA
GO:1900026,BP,"positive regulation of substrate adhesion-dependent cell spreading","Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.",IEA