go_id,ontology,go_term,term_definition,evidence
GO:0000287,MF,"magnesium ion binding","Interacting selectively and non-covalently with magnesium (Mg) ions.",IDA
GO:0004477,MF,"methenyltetrahydrofolate cyclohydrolase activity","Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.",TAS
GO:0004487,MF,"methylenetetrahydrofolate dehydrogenase (NAD+) activity","Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.",ISS
GO:0004488,MF,"methylenetetrahydrofolate dehydrogenase (NADP+) activity","Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.",IBA
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA
GO:0005759,CC,"mitochondrial matrix","The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",TAS
GO:0006730,BP,"one-carbon metabolic process","The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.",IEA
GO:0009396,BP,"folic acid-containing compound biosynthetic process","The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.",IEA
GO:0042301,MF,"phosphate ion binding","Interacting selectively and non-covalently with phosphate.",IDA
GO:0046653,BP,"tetrahydrofolate metabolic process","The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.",IDA
GO:0046655,BP,"folic acid metabolic process","The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.",TAS
GO:0055114,BP,"oxidation-reduction process","A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.",IEA