go_id,ontology,go_term,term_definition,evidence
GO:0000122,BP,"negative regulation of transcription from RNA polymerase II promoter","Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA|ISS
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA
GO:0007346,BP,"regulation of mitotic cell cycle","Any process that modulates the rate or extent of progress through the mitotic cell cycle.",IMP
GO:0008284,BP,"positive regulation of cell proliferation","Any process that activates or increases the rate or extent of cell proliferation.",IMP
GO:0008285,BP,"negative regulation of cell proliferation","Any process that stops, prevents or reduces the rate or extent of cell proliferation.",NAS
GO:0015629,CC,"actin cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.",ISS
GO:0030154,BP,"cell differentiation","The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.",IEA
GO:0030335,BP,"positive regulation of cell migration","Any process that activates or increases the frequency, rate or extent of cell migration.",IMP
GO:0043065,BP,"positive regulation of apoptotic process","Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.",ISS
GO:0043066,BP,"negative regulation of apoptotic process","Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.",IMP
GO:0045597,BP,"positive regulation of cell differentiation","Any process that activates or increases the frequency, rate or extent of cell differentiation.",IEA
GO:0046022,BP,"positive regulation of transcription from RNA polymerase II promoter during mitosis","Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis.",IMP
GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA
GO:0071157,BP,"negative regulation of cell cycle arrest","Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.",IEA