go_id,ontology,go_term,term_definition,evidence GO:0000122,BP,"negative regulation of transcription from RNA polymerase II promoter","Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA|ISS GO:0002244,BP,"hematopoietic progenitor cell differentiation","The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.",IEA GO:0004871,MF,"signal transducer activity","Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.",IMP GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005576,CC,"extracellular region","The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.",IEA GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA GO:0032926,BP,"negative regulation of activin receptor signaling pathway","Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.",IDA GO:0043395,MF,"heparan sulfate proteoglycan binding","Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.",IEA GO:0048185,MF,"activin binding","Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.",IPI GO:0051798,BP,"positive regulation of hair follicle development","Any process that activates or increases the frequency, rate or extent of hair follicle development.",IEA