go_id,ontology,go_term,term_definition,evidence GO:0000812,CC,"Swr1 complex","A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.",IBA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0031063,BP,"regulation of histone deacetylation","Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.",IBA GO:0031491,MF,"nucleosome binding","Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.",IEA GO:0042826,MF,"histone deacetylase binding","Interacting selectively and non-covalently with the enzyme histone deacetylase.",IPI GO:0043486,BP,"histone exchange","The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.",IBA GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA