go_id,ontology,go_term,term_definition,evidence
GO:0002376,BP,"immune system process","Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.",IEA
GO:0005136,MF,"interleukin-4 receptor binding","Interacting selectively and non-covalently with the interleukin-4 receptor.",IDA
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005813,CC,centrosome,"A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.",IDA
GO:0007080,BP,"mitotic metaphase plate congression","The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.",IMP
GO:0010531,BP,"activation of JAK1 kinase activity","The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.",IDA
GO:0031393,BP,"negative regulation of prostaglandin biosynthetic process","Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",IDA
GO:0032695,BP,"negative regulation of interleukin-12 production","Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.",IDA
GO:0032733,BP,"positive regulation of interleukin-10 production","Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.",ISS
GO:0032815,BP,"negative regulation of natural killer cell activation","Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.",IDA
GO:0034451,CC,"centriolar satellite","A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.",ISS
GO:0035058,BP,"nonmotile primary cilium assembly","The assembly of a primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules.",IMP
GO:0042521,BP,"negative regulation of tyrosine phosphorylation of Stat4 protein","Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat4 protein.",IDA
GO:0042526,BP,"positive regulation of tyrosine phosphorylation of Stat6 protein","Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat6 protein.",IDA
GO:0071539,BP,"protein localization to centrosome","A process in which a protein is transported to, or maintained at, the centrosome.",IEA
GO:0090307,BP,"mitotic spindle assembly","The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.",IMP