go_id,ontology,go_term,term_definition,evidence
GO:0000122,BP,"negative regulation of transcription from RNA polymerase II promoter","Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA|ISS
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0006325,BP,"chromatin organization","Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.",TAS
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA
GO:0016569,BP,"chromatin modification","The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.",IEA
GO:0045665,BP,"negative regulation of neuron differentiation","Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.",IEA
GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI