go_id,ontology,go_term,term_definition,evidence GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0006886,BP,"intracellular protein transport","The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.",IEA GO:0006914,BP,autophagy,"The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.",TAS GO:0016197,BP,"endosomal transport","The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.",TAS GO:0031901,CC,"early endosome membrane","The lipid bilayer surrounding an early endosome.",IEA GO:0033565,CC,"ESCRT-0 complex","A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.",TAS GO:0036258,BP,"multivesicular body assembly","The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.",TAS GO:0042059,BP,"negative regulation of epidermal growth factor receptor signaling pathway","Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.",TAS GO:0043231,CC,"intracellular membrane-bounded organelle","Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",IDA