go_id,ontology,go_term,term_definition,evidence
GO:0000375,BP,"RNA splicing, via transesterification reactions","Splicing of RNA via a series of two transesterification reactions.",TAS
GO:0000398,BP,"mRNA splicing, via spliceosome","The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.",IGI
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0006369,BP,"termination of RNA polymerase II transcription","The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.",TAS
GO:0006405,BP,"RNA export from nucleus","The directed movement of RNA from the nucleus to the cytoplasm.",TAS
GO:0006406,BP,"mRNA export from nucleus","The directed movement of mRNA from the nucleus to the cytoplasm.",IGI
GO:0008380,BP,"RNA splicing","The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.",IEA
GO:0016363,CC,"nuclear matrix","The dense fibrillar network lying on the inner side of the nuclear membrane.",IEA
GO:0016607,CC,"nuclear speck","A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.",IEA
GO:0031124,BP,"mRNA 3'-end processing","Any process involved in forming the mature 3' end of an mRNA molecule.",TAS
GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA
GO:0071013,CC,"catalytic step 2 spliceosome","A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.",IDA