go_id,ontology,go_term,term_definition,evidence
GO:0005200,MF,"structural constituent of cytoskeleton","The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.",IBA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0005885,CC,"Arp2/3 protein complex","A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.",IDA
GO:0005925,CC,"focal adhesion","Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.",IDA
GO:0006928,BP,"movement of cell or subcellular component","The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.",TAS
GO:0015629,CC,"actin cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.",ISS
GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA
GO:0030027,CC,lamellipodium,"A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.",IEA
GO:0030426,CC,"growth cone","The migrating motile tip of a growing nerve cell axon or dendrite.",IDA
GO:0034314,BP,"Arp2/3 complex-mediated actin nucleation","The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.",IDA|ISS
GO:0038096,BP,"Fc-gamma receptor signaling pathway involved in phagocytosis","An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.",TAS
GO:0048013,BP,"ephrin receptor signaling pathway","The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.",TAS
GO:0051015,MF,"actin filament binding","Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.",IBA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:1990090,BP,"cellular response to nerve growth factor stimulus","A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.",IEA