go_id,ontology,go_term,term_definition,evidence
GO:0000302,BP,"response to reactive oxygen species","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.",TAS
GO:0004602,MF,"glutathione peroxidase activity","Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.",IBA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005764,CC,lysosome,"A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.",IBA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0005913,CC,"cell-cell adherens junction","An adherens junction which connects a cell to another cell.",IDA
GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA
GO:0016023,CC,"cytoplasmic, membrane-bounded vesicle","A membrane-bounded vesicle found in the cytoplasm of the cell.",IEA
GO:0016042,BP,"lipid catabolic process","The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.",IEA
GO:0016787,MF,"hydrolase activity","Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.",IEA
GO:0031625,MF,"ubiquitin protein ligase binding","Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.",IBA
GO:0042744,BP,"hydrogen peroxide catabolic process","The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).",IDA
GO:0045454,BP,"cell redox homeostasis","Any process that maintains the redox environment of a cell or compartment within a cell.",IMP
GO:0051920,MF,"peroxiredoxin activity","Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.",IEA
GO:0055114,BP,"oxidation-reduction process","A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:0098609,BP,"cell-cell adhesion","The attachment of one cell to another cell via adhesion molecules.",IEA
GO:0098641,MF,"cadherin binding involved in cell-cell adhesion","Any cadherin binding that occurs as part of the process of cell-cell adhesion.",IDA
GO:0098869,BP,"cellular oxidant detoxification","Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.",IEA