go_id,ontology,go_term,term_definition,evidence
GO:0001817,BP,"regulation of cytokine production","Any process that modulates the frequency, rate, or extent of production of a cytokine.",ISS
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0005887,CC,"integral component of plasma membrane","The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IDA
GO:0006952,BP,"defense response","Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.",TAS
GO:0006959,BP,"humoral immune response","An immune response mediated through a body fluid.",IEA
GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA
GO:0009897,CC,"external side of plasma membrane","The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.",IBA
GO:0014070,BP,"response to organic cyclic compound","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.",IEA
GO:0032713,BP,"negative regulation of interleukin-4 production","Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.",IEA
GO:0032733,BP,"positive regulation of interleukin-10 production","Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.",ISS
GO:0032743,BP,"positive regulation of interleukin-2 production","Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.",IMP
GO:0043372,BP,"positive regulation of CD4-positive, alpha-beta T cell differentiation","Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.",IEA