go_id,ontology,go_term,term_definition,evidence
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003725,MF,"double-stranded RNA binding","Interacting selectively and non-covalently with double-stranded RNA.",IDA|NAS
GO:0005575,CC,cellular_component,"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.",ND
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0005856,CC,cytoskeleton,"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.",IBA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0005913,CC,"cell-cell adherens junction","An adherens junction which connects a cell to another cell.",IDA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006357,BP,"regulation of transcription from RNA polymerase II promoter","Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.",TAS
GO:0008150,BP,biological_process,"Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.",ND
GO:0032481,BP,"positive regulation of type I interferon production","Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",TAS
GO:0042803,MF,"protein homodimerization activity","Interacting selectively and non-covalently with an identical protein to form a homodimer.",IEA
GO:0045892,BP,"negative regulation of transcription, DNA-templated","Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.",ISS
GO:0051092,BP,"positive regulation of NF-kappaB transcription factor activity","Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.",IDA
GO:0098609,BP,"cell-cell adhesion","The attachment of one cell to another cell via adhesion molecules.",IEA
GO:0098641,MF,"cadherin binding involved in cell-cell adhesion","Any cadherin binding that occurs as part of the process of cell-cell adhesion.",IDA