go_id,ontology,go_term,term_definition,evidence GO:0000226,BP,"microtubule cytoskeleton organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.",IBA|ISS GO:0005102,MF,"receptor binding","Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.",IPI GO:0005198,MF,"structural molecule activity","The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.",IBA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005874,CC,microtubule,"Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.",IEA GO:0005875,CC,"microtubule associated complex","Any multimeric complex connected to a microtubule.",TAS GO:0006970,BP,"response to osmotic stress","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",IDA GO:0007163,BP,"establishment or maintenance of cell polarity","Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.",IEA GO:0015630,CC,"microtubule cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.",IDA GO:0016323,CC,"basolateral plasma membrane","The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.",IEA GO:0048471,CC,"perinuclear region of cytoplasm","Cytoplasm situated near, or occurring around, the nucleus.",IDA GO:0072659,BP,"protein localization to plasma membrane","A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.",IEA