go_id,ontology,go_term,term_definition,evidence
GO:0001731,BP,"formation of translation preinitiation complex","The joining of the small ribosomal subunit, ternary complex, and mRNA.",IDA
GO:0002181,BP,"cytoplasmic translation","The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.",IBA
GO:0003743,MF,"translation initiation factor activity","Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.",IEA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0005852,CC,"eukaryotic translation initiation factor 3 complex","A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.",IDA
GO:0006413,BP,"translational initiation","The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.",IEA
GO:0006446,BP,"regulation of translational initiation","Any process that modulates the frequency, rate or extent of translational initiation.",IMP
GO:0016282,CC,"eukaryotic 43S preinitiation complex","A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.",IEA
GO:0033290,CC,"eukaryotic 48S preinitiation complex","A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.",IEA