go_id,ontology,go_term,term_definition,evidence
GO:0004114,MF,"3',5'-cyclic-nucleotide phosphodiesterase activity","Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.",IEA
GO:0005575,CC,cellular_component,"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.",ND
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA
GO:0010613,BP,"positive regulation of cardiac muscle hypertrophy","Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.",IEA
GO:0030553,MF,"cGMP binding","Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).",TAS
GO:0030823,BP,"regulation of cGMP metabolic process","Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.",IEA
GO:0042130,BP,"negative regulation of T cell proliferation","Any process that stops, prevents or reduces the rate or extent of T cell proliferation.",ISS
GO:0043406,BP,"positive regulation of MAP kinase activity","Any process that activates or increases the frequency, rate or extent of MAP kinase activity.",IDA
GO:0046069,BP,"cGMP catabolic process","The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.",IDA|IEA
GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA
GO:0047555,MF,"3',5'-cyclic-GMP phosphodiesterase activity","Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.",TAS
GO:0055118,BP,"negative regulation of cardiac muscle contraction","Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.",IEA
GO:0055119,BP,"relaxation of cardiac muscle","The process in which the extent of cardiac muscle contraction is reduced.",IEA
GO:0060282,BP,"positive regulation of oocyte development","Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",IEA