go_id,ontology,go_term,term_definition,evidence
GO:0000151,CC,"ubiquitin ligase complex","A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.",IBA
GO:0000287,MF,"magnesium ion binding","Interacting selectively and non-covalently with magnesium (Mg) ions.",IDA
GO:0004674,MF,"protein serine/threonine kinase activity","Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",IBA
GO:0004712,MF,"protein serine/threonine/tyrosine kinase activity","Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.",TAS
GO:0004713,MF,"protein tyrosine kinase activity","Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.",IEA
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0006468,BP,"protein phosphorylation","The process of introducing a phosphate group on to a protein.",NAS
GO:0006974,BP,"cellular response to DNA damage stimulus","Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.",IMP
GO:0007224,BP,"smoothened signaling pathway","A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.",IEA
GO:0018108,BP,"peptidyl-tyrosine phosphorylation","The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.",IEA
GO:0030145,MF,"manganese ion binding","Interacting selectively and non-covalently with manganese (Mn) ions.",IEA
GO:0030529,CC,"intracellular ribonucleoprotein complex","An intracellular macromolecular complex containing both protein and RNA molecules.",IDA
GO:0042771,BP,"intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.",IEA
GO:0043130,MF,"ubiquitin binding","Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.",IBA
GO:0045725,BP,"positive regulation of glycogen biosynthetic process","Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.",IDA
GO:0051534,BP,"negative regulation of NFAT protein import into nucleus","Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.",IMP
GO:1901796,BP,"regulation of signal transduction by p53 class mediator","Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.",TAS