go_id,ontology,go_term,term_definition,evidence
GO:0000166,MF,"nucleotide binding","Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA
GO:0005741,CC,"mitochondrial outer membrane","The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.",IDA
GO:0005743,CC,"mitochondrial inner membrane","The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.",IEA
GO:0006820,BP,"anion transport","The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",TAS
GO:0008021,CC,"synaptic vesicle","A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.",IDA
GO:0008308,MF,"voltage-gated anion channel activity","Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.",IDA
GO:0015288,MF,"porin activity","Catalysis of the transfer of substances, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.",NAS
GO:0032272,BP,"negative regulation of protein polymerization","Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.",IEA
GO:0042645,CC,"mitochondrial nucleoid","The region of a mitochondrion to which the DNA is confined.",IBA
GO:0043209,CC,"myelin sheath","An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.",IEA
GO:0046930,CC,"pore complex","Any small opening in a membrane that allows the passage of gases and/or liquids.",IEA
GO:0055085,BP,"transmembrane transport","The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:1903959,BP,"regulation of anion transmembrane transport","Any process that modulates the frequency, rate or extent of anion transmembrane transport.",IEA
GO:2001243,BP,"negative regulation of intrinsic apoptotic signaling pathway","Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.",IMP