go_id,ontology,go_term,term_definition,evidence
GO:0003684,MF,"damaged DNA binding","Interacting selectively and non-covalently with damaged DNA.",TAS
GO:0004844,MF,"uracil DNA N-glycosylase activity","Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.",NAS|TAS
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0006281,BP,"DNA repair","The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.",IEA
GO:0006284,BP,"base-excision repair","In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.",IDA
GO:0016032,BP,"viral process","A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.",IEA
GO:0016446,BP,"somatic hypermutation of immunoglobulin genes","Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.",ISS
GO:0016447,BP,"somatic recombination of immunoglobulin gene segments","The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.",IEA
GO:0019899,MF,"enzyme binding","Interacting selectively and non-covalently with any enzyme.",IPI
GO:0043066,BP,"negative regulation of apoptotic process","Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.",IMP
GO:0045008,BP,depyrimidination,"The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.",TAS
GO:0045830,BP,"positive regulation of isotype switching","Any process that activates or increases the frequency, rate or extent of isotype switching.",IDA
GO:0097510,BP,"base-excision repair, AP site formation via deaminated base removal","A base-excision repair, AP site formation process occurring via excision of a deaminated base.",IDA