go_id,ontology,go_term,term_definition,evidence
GO:0005201,MF,"extracellular matrix structural constituent","The action of a molecule that contributes to the structural integrity of the extracellular matrix.",IBA
GO:0005518,MF,"collagen binding","Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).",IEA
GO:0005576,CC,"extracellular region","The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.",IEA
GO:0005578,CC,"proteinaceous extracellular matrix","A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.",IEA
GO:0005581,CC,"collagen trimer","A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.",IEA
GO:0005596,CC,"collagen type XIV trimer","A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.",NAS
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005788,CC,"endoplasmic reticulum lumen","The volume enclosed by the membranes of the endoplasmic reticulum.",IDA
GO:0016337,BP,"single organismal cell-cell adhesion","The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.",NAS
GO:0030198,BP,"extracellular matrix organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.",IEA
GO:0030199,BP,"collagen fibril organization","Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.",IMP
GO:0030674,MF,"protein binding, bridging","The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.",NAS
GO:0031012,CC,"extracellular matrix","A structure lying external to one or more cells, which provides structural support for cells or tissues.",IDA|ISS
GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA