go_id,ontology,go_term,term_definition,evidence
GO:0001869,BP,"negative regulation of complement activation, lectin pathway","Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.",IDA
GO:0002576,BP,"platelet degranulation","The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.",TAS
GO:0004867,MF,"serine-type endopeptidase inhibitor activity","Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.",IDA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005576,CC,"extracellular region","The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.",IEA
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0006958,BP,"complement activation, classical pathway","Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.",IBA
GO:0007568,BP,aging,"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).",IEA
GO:0007597,BP,"blood coagulation, intrinsic pathway","A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.",TAS
GO:0008015,BP,"blood circulation","The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.",TAS
GO:0010951,BP,"negative regulation of endopeptidase activity","Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.",IEA
GO:0031093,CC,"platelet alpha granule lumen","The volume enclosed by the membrane of the platelet alpha granule.",TAS
GO:0042730,BP,fibrinolysis,"A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.",IDA
GO:0045087,BP,"innate immune response","Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.",IBA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:0072562,CC,"blood microparticle","A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.",IBA