go_id,ontology,go_term,term_definition,evidence GO:0003779,MF,"actin binding","Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.",IEA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005862,CC,"muscle thin filament tropomyosin","A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.",TAS GO:0006936,BP,"muscle contraction","A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.",TAS GO:0008307,MF,"structural constituent of muscle","The action of a molecule that contributes to the structural integrity of a muscle fiber.",NAS GO:0030049,BP,"muscle filament sliding","The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.",TAS GO:0043462,BP,"regulation of ATPase activity","Any process that modulates the rate of ATP hydrolysis by an ATPase.",IDA