go_id,ontology,go_term,term_definition,evidence
GO:0001518,CC,"voltage-gated sodium channel complex","A sodium channel in a cell membrane whose opening is governed by the membrane potential.",IEA
GO:0005248,MF,"voltage-gated sodium channel activity","Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.",IDA
GO:0005887,CC,"integral component of plasma membrane","The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IDA
GO:0006814,BP,"sodium ion transport","The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",IEA
GO:0006954,BP,"inflammatory response","The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.",IBA
GO:0009636,BP,"response to toxic substance","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.",IEA
GO:0009791,BP,"post-embryonic development","The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.",IEA
GO:0019228,BP,"neuronal action potential","An action potential that occurs in a neuron.",ISS
GO:0019233,BP,"sensory perception of pain","The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.",IEA
GO:0031402,MF,"sodium ion binding","Interacting selectively and non-covalently with sodium ions (Na+).",IDA
GO:0034765,BP,"regulation of ion transmembrane transport","Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.",IEA
GO:0035725,BP,"sodium ion transmembrane transport","A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.",IDA
GO:0042995,CC,"cell projection","A prolongation or process extending from a cell, e.g. a flagellum or axon.",IEA
GO:0048266,BP,"behavioral response to pain","Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.",ISS
GO:0060078,BP,"regulation of postsynaptic membrane potential","Any process that modulates the potential difference across a post-synaptic membrane.",IEA
GO:0086010,BP,"membrane depolarization during action potential","The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.",IBA