go_id,ontology,go_term,term_definition,evidence GO:0005080,MF,"protein kinase C binding","Interacting selectively and non-covalently with protein kinase C.",IEA GO:0005509,MF,"calcium ion binding","Interacting selectively and non-covalently with calcium ions (Ca2+).",IDA GO:0005622,CC,intracellular,"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.",IEA GO:0005783,CC,"endoplasmic reticulum","The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).",IDA GO:0005788,CC,"endoplasmic reticulum lumen","The volume enclosed by the membranes of the endoplasmic reticulum.",IDA GO:0006457,BP,"protein folding","The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.",IEA GO:0006491,BP,"N-glycan processing","The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.",IEA GO:0035556,BP,"intracellular signal transduction","The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.",IEA GO:0044325,MF,"ion channel binding","Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.",ISS GO:0051219,MF,"phosphoprotein binding","Interacting selectively and non-covalently with a phosphorylated protein.",IPI