go_id,ontology,go_term,term_definition,evidence
GO:0000275,CC,"mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)","The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.",IBA|NAS
GO:0005215,MF,"transporter activity","Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.",IEA
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA
GO:0005743,CC,"mitochondrial inner membrane","The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.",IEA
GO:0005753,CC,"mitochondrial proton-transporting ATP synthase complex","A proton-transporting ATP synthase complex found in the mitochondrial membrane.",IDA
GO:0005759,CC,"mitochondrial matrix","The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",TAS
GO:0006119,BP,"oxidative phosphorylation","The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.",TAS
GO:0006754,BP,"ATP biosynthetic process","The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",TAS
GO:0015986,BP,"ATP synthesis coupled proton transport","The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.",IBA
GO:0016887,MF,"ATPase activity","Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.",IEA
GO:0022857,MF,"transmembrane transporter activity","Enables the transfer of a substance from one side of a membrane to the other.",IC
GO:0042776,BP,"mitochondrial ATP synthesis coupled proton transport","The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.",IC|TAS
GO:0043531,MF,"ADP binding","Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate.",IDA
GO:0046688,BP,"response to copper ion","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.",IDA
GO:0046933,MF,"proton-transporting ATP synthase activity, rotational mechanism","Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.",IBA
GO:0046961,MF,"proton-transporting ATPase activity, rotational mechanism","Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.",TAS