go_id,ontology,go_term,term_definition,evidence GO:0001525,BP,angiogenesis,"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.",IEA GO:0001786,MF,"phosphatidylserine binding","Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.",IDA GO:0004435,MF,"phosphatidylinositol phospholipase C activity","Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).",IDA GO:0004871,MF,"signal transducer activity","Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.",IMP GO:0005509,MF,"calcium ion binding","Interacting selectively and non-covalently with calcium ions (Ca2+).",IDA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0006644,BP,"phospholipid metabolic process","The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.",IBA GO:0016042,BP,"lipid catabolic process","The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.",IEA GO:0032794,MF,"GTPase activating protein binding","Interacting selectively and non-covalently with a GTPase activating protein.",IEA GO:0035556,BP,"intracellular signal transduction","The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.",IEA GO:0042127,BP,"regulation of cell proliferation","Any process that modulates the frequency, rate or extent of cell proliferation.",IBA GO:0043647,BP,"inositol phosphate metabolic process","The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",TAS GO:0060716,BP,"labyrinthine layer blood vessel development","The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.",IEA GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA GO:0070300,MF,"phosphatidic acid binding","Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.",IEA GO:1901981,MF,"phosphatidylinositol phosphate binding","Interacting selectively and non-covalently with phosphatidylinositol phosphate.",IEA