go_id,ontology,go_term,term_definition,evidence
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA
GO:0016602,CC,"CCAAT-binding factor complex","A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.",IDA
GO:0032403,MF,"protein complex binding","Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IEA
GO:0032993,CC,"protein-DNA complex","A macromolecular complex containing both protein and DNA molecules.",IEA
GO:0043565,MF,"sequence-specific DNA binding","Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",ISS
GO:0044212,MF,"transcription regulatory region DNA binding","Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.",IDA
GO:0045893,BP,"positive regulation of transcription, DNA-templated","Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.",IDA
GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI
GO:0070491,MF,"repressing transcription factor binding","Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.",IPI