go_id,ontology,go_term,term_definition,evidence GO:0005743,CC,"mitochondrial inner membrane","The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.",IEA GO:0005747,CC,"mitochondrial respiratory chain complex I","A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.",IDA|IMP|NAS GO:0006120,BP,"mitochondrial electron transport, NADH to ubiquinone","The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.",NAS|TAS GO:0006631,BP,"fatty acid metabolic process","The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.",IEA GO:0006936,BP,"muscle contraction","A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.",TAS GO:0008137,MF,"NADH dehydrogenase (ubiquinone) activity","Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.",IMP|NAS GO:0009055,MF,"electron carrier activity","Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.",TAS GO:0010259,BP,"multicellular organism aging","An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).",IEA GO:0032981,BP,"mitochondrial respiratory chain complex I assembly","The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.",IMP|TAS GO:0035264,BP,"multicellular organism growth","The increase in size or mass of an entire multicellular organism, as opposed to cell growth.",IEA GO:0061458,BP,"reproductive system development","The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.",IEA GO:0070584,BP,"mitochondrion morphogenesis","The process in which the anatomical structures of a mitochondrion are generated and organized.",IEA GO:0072358,BP,"cardiovascular system development","The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.",IEA