go_id,ontology,go_term,term_definition,evidence
GO:0002026,BP,"regulation of the force of heart contraction","Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.",IEA
GO:0003785,MF,"actin monomer binding","Interacting selectively and non-covalently with monomeric actin, also known as G-actin.",IDA
GO:0005509,MF,"calcium ion binding","Interacting selectively and non-covalently with calcium ions (Ca2+).",IDA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0016459,CC,"myosin complex","A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.",IEA
GO:0030049,BP,"muscle filament sliding","The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.",TAS
GO:0031672,CC,"A band","The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.",ISS
GO:0032038,MF,"myosin II heavy chain binding","Interacting selectively and non-covalently with a heavy chain of a myosin II complex.",NAS
GO:0032781,BP,"positive regulation of ATPase activity","Any process that activates or increases the rate of ATP hydrolysis by an ATPase.",IEA
GO:0051015,MF,"actin filament binding","Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.",IBA
GO:0060048,BP,"cardiac muscle contraction","Muscle contraction of cardiac muscle tissue.",ISS