go_id,ontology,go_term,term_definition,evidence
GO:0000139,CC,"Golgi membrane","The lipid bilayer surrounding any of the compartments of the Golgi apparatus.",IEA
GO:0003924,MF,"GTPase activity","Catalysis of the reaction: GTP + H2O = GDP + phosphate.",IEA
GO:0004842,MF,"ubiquitin-protein transferase activity","Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.",IBA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005525,MF,"GTP binding","Interacting selectively and non-covalently with GTP, guanosine triphosphate.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005765,CC,"lysosomal membrane","The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.",TAS
GO:0007264,BP,"small GTPase mediated signal transduction","Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.",IEA
GO:0008047,MF,"enzyme activator activity","Binds to and increases the activity of an enzyme.",IDA
GO:0008270,MF,"zinc ion binding","Interacting selectively and non-covalently with zinc (Zn) ions.",IEA
GO:0016032,BP,"viral process","A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.",IEA
GO:0016567,BP,"protein ubiquitination","The process in which one or more ubiquitin groups are added to a protein.",IMP
GO:0016874,MF,"ligase activity","Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",IEA
GO:0019003,MF,"GDP binding","Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.",IDA
GO:0042802,MF,"identical protein binding","Interacting selectively and non-covalently with an identical protein or proteins.",IEA
GO:0043085,BP,"positive regulation of catalytic activity","Any process that activates or increases the activity of an enzyme.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA