go_id,ontology,go_term,term_definition,evidence
GO:0000226,BP,"microtubule cytoskeleton organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.",IBA|ISS
GO:0000287,MF,"magnesium ion binding","Interacting selectively and non-covalently with magnesium (Mg) ions.",IDA
GO:0001764,BP,"neuron migration","The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.",IEA
GO:0001786,MF,"phosphatidylserine binding","Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.",IDA
GO:0004674,MF,"protein serine/threonine kinase activity","Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",IBA
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005546,MF,"phosphatidylinositol-4,5-bisphosphate binding","Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.",ISS
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005856,CC,cytoskeleton,"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.",IBA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0006468,BP,"protein phosphorylation","The process of introducing a phosphate group on to a protein.",NAS
GO:0007010,BP,"cytoskeleton organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.",IEA
GO:0015630,CC,"microtubule cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.",IDA
GO:0016055,BP,"Wnt signaling pathway","The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.",IEA
GO:0030010,BP,"establishment of cell polarity","The specification and formation of anisotropic intracellular organization or cell growth patterns.",IEA
GO:0035556,BP,"intracellular signal transduction","The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.",IEA
GO:0050321,MF,"tau-protein kinase activity","Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.",IEA
GO:0070300,MF,"phosphatidic acid binding","Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.",IEA