go_id,ontology,go_term,term_definition,evidence GO:0000250,MF,"lanosterol synthase activity","Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.",IGI|IMP|TAS GO:0005789,CC,"endoplasmic reticulum membrane","The lipid bilayer surrounding the endoplasmic reticulum.",IEA GO:0005811,CC,"lipid particle","An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.",NAS|TAS GO:0006694,BP,"steroid biosynthetic process","The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.",TAS GO:0006695,BP,"cholesterol biosynthetic process","The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",IEA GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA GO:0031647,BP,"regulation of protein stability","Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.",IMP